Description

Avanafil CAS NO 330784-47-9 is a potent and selective phosphodiesterase type 5 (PDE5) inhibitor. This active pharmaceutical ingredient (API) is critical for the formulation of medications used to treat erectile dysfunction, offering a rapid onset of action and favorable side-effect profile. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of advanced urological therapeutics.

Application

• Primary Active Pharmaceutical Ingredient (API) for the manufacture of prescription medications targeting erectile dysfunction (ED).
• Key intermediate in advanced pharmaceutical research for novel PDE5 inhibitor formulations.
• Reference standard for quality control and analytical testing in pharmaceutical laboratories.
• Raw material for clinical trial material (CTM) production in urological drug development.
• Component in preclinical studies investigating cardiovascular and pulmonary applications of PDE5 inhibition.

Basic Information

Product Name	Avanafil
CAS No.	330784-47-9
Molecular Formula	C23H26ClN7O3
Molecular Weight	483.95 g/mol
Synonyms	4-[(3-Chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide; Stendra; Vivus; TA-1790
EINECS	Contact for details

Quality Control

Our Avanafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Certificates of Analysis (COA) detailing specifications for identity, purity, and impurities are provided and can be tailored to meet specific pharmacopeial requirements (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container in a well-ventilated area and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.