Description

Enclomiphene is a non-steroidal selective estrogen receptor modulator (SERM) and the *trans* isomer of clomiphene citrate. This compound is of significant interest for its potential role in stimulating endogenous testosterone production. It is primarily utilized in pharmaceutical research and development, particularly for applications in endocrinology and male reproductive health. Global demand is driven by its use as a key intermediate in the synthesis of advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of therapeutic compounds targeting hormone regulation.
• Endocrine Research: Used in preclinical and clinical studies investigating treatments for conditions like hypogonadism and infertility.
• Selective Estrogen Receptor Modulator (SERM) Studies: Serves as a reference standard and active material in SERM mechanism of action and efficacy research.
• API Development: Employed in the development and scale-up of Active Pharmaceutical Ingredients (APIs) for hormonal therapies.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing via HPLC or LC-MS.
• Biochemical Research: Applied in studies of estrogen receptor binding and signal transduction pathways.

Basic Information

Product Name	Enclomiphene
CAS No.	15690-57-0
Molecular Formula	C26H28ClNO
Molecular Weight	405.96 g/mol
Synonyms	trans-Clomiphene; Enclomifene; (E)-Clomiphene; Zuclomiphene isomer; 2-[4-[(E)-2-Chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine; Androxal (developmental drug name); ERC-007
EINECS	Contact for details

Quality Control

Our Enclomiphene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling to ensure it meets stringent specifications for pharmaceutical research. Certificates of Analysis (COA) detailing results from HPLC, NMR, and other relevant tests are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.