Description

Bremelanotide is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH) that acts as a potent and selective agonist of the melanocortin 4 receptor (MC4R). This compound is of significant commercial and research interest due to its well-characterized pharmacological profile and its role in modulating energy homeostasis and sexual function. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) for the development of therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and intermediate in the development of novel therapeutics targeting metabolic disorders and sexual dysfunction.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the controlled synthesis of finished dosage forms for clinical and commercial applications.
• Biochemical Research: A critical tool for studying melanocortin receptor signaling pathways, ligand-receptor interactions, and central nervous system physiology.
• Preclinical Studies: Employed in animal models to investigate effects on appetite, energy expenditure, and sexual arousal for proof-of-concept studies.
• Quality Control Laboratories: Functions as a high-purity analytical standard for method development, validation, and batch release testing in GMP environments.

Basic Information

Product Name	Bremelanotide
CAS No.	189691-06-3
Molecular Formula	C50H68N14O10
Molecular Weight	1025.2 g/mol
Synonyms	PT-141; [Nle4, D-Phe7]-α-MSH; Melanotan II; Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2; Bremelanotide Acetate; Vyleesi (brand name); Melanocortin 4 Receptor Agonist
EINECS	Contact for details

Quality Control

Our Bremelanotide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and tests for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications and results are provided to ensure compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	5.0% - 12.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.