Description

Yohimbine Hydrochloride is a crystalline alkaloid salt derived from the bark of the *Pausinystalia yohimbe* tree. This compound is valued for its specific pharmacological activity as a selective α2-adrenergic receptor antagonist. It serves as a critical active pharmaceutical ingredient (API) and research biochemical for pharmaceutical development, nutraceutical formulation, and life science research.

Application

• Pharmaceutical Active Ingredient (API): Used in the formulation of prescription medications and clinical research compounds.
• Nutraceutical & Dietary Supplement Formulation: A key component in supplements targeting specific metabolic support.
• Biochemical & Life Science Research: Employed as a selective α2-adrenergic blocker in pharmacological, neurological, and physiological studies.
• Reference Standard: Serves as a high-purity standard for analytical testing and quality control in laboratories.
• Veterinary Pharmaceutical Applications: Used in certain veterinary medicinal products.

Basic Information

Product Name	Yohimbine Hydrochloride
CAS No.	65-19-0
Molecular Formula	C21H26N2O3·HCl
Molecular Weight	390.90 g/mol
Synonyms	Yohimbine HCl; Quebrachine Hydrochloride; Aphrodine; Corynine Hydrochloride; 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride; (16α,17α)-17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride
EINECS	200-603-5

Quality Control

Our Yohimbine Hydrochloride is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with industry standards for pharmaceutical ingredients. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.