Description

Propoxyphenyl Homohydroxysildenafil is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the development and synthesis of specialized active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in advanced drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for pharmacological studies and structure-activity relationship (SAR) analysis.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes during drug development phases.
• Biochemical Research: Utilized in studies investigating specific enzyme interactions and receptor binding assays.

Basic Information

Product Name	Propoxyphenyl Homohydroxysildenafil
CAS No.	139755-87-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine; Homohydroxysildenafil; Propoxyphenyl Hydroxysildenafil; Sildenafil Impurity; Sildenafil Related Compound; PDE5 Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our Propoxyphenyl Homohydroxysildenafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.