Description

5-(2-Ethoxyphenyl)-1-Methyl-3-n-Propyl-1,6-Dihydro-7H-Pyrazolo[4,3-D]-7-Pyrimidinone is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidinone class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of novel small-molecule drugs.
• Biochemical Research: Employed in biochemical assays and as a tool compound for investigating specific biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5-(2-Ethoxyphenyl)-1-Methyl-3-n-Propyl-1,6-Dihydro-7H-Pyrazolo[4,3-D]-7-Pyrimidinone
CAS No.	139756-21-1
Molecular Formula	C₁₇H₂₀N₄O₂
Molecular Weight	312.37 g/mol
Synonyms	5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; 1-Methyl-3-propyl-5-(2-ethoxyphenyl)-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; Tadalafil Impurity; Tadalafil Related Compound; Pyrazolo[4,3-d]pyrimidin-7-one derivative; PDE5 Inhibitor Intermediate; 139756-21-1
EINECS	Contact for details

Quality Control

Our 5-(2-Ethoxyphenyl)-1-Methyl-3-n-Propyl-1,6-Dihydro-7H-Pyrazolo[4,3-D]-7-Pyrimidinone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.