Description

3-Bromo Pirfenidone is a halogenated derivative of the anti-fibrotic agent Pirfenidone, serving as a crucial synthetic intermediate and research chemical. This compound matters for its role in the development and study of novel pharmaceutical compounds, particularly in modifying the core Pirfenidone structure to explore new therapeutic pathways. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of advanced drug candidates targeting fibrotic diseases and other conditions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Pirfenidone analogs and derivatives for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to investigate the impact of bromination on biological activity and pharmacokinetic properties.
• Reference Standard: Serves as an analytical standard for quality control and method development in the production of related active pharmaceutical ingredients (APIs).
• Biochemical Tool: Employed in in-vitro and in-vivo research models to study fibrosis mechanisms and evaluate potential anti-fibrotic effects.
• Process Chemistry: Utilized in route scouting and optimization for the scalable synthesis of complex organic molecules in fine chemical production.

Basic Information

Product Name	3-Bromo Pirfenidone
CAS No.	912570-13-9
Molecular Formula	C12H10BrNO2
Molecular Weight	280.12 g/mol
Synonyms	5-Methyl-1-(3-bromophenyl)-2(1H)-pyridone; 1-(3-Bromophenyl)-5-methyl-2(1H)-pyridinone; 3-Bromo-5-methyl-1-phenyl-2(1H)-pyridinone; 3-Bromopirfenidone; 3-Br-Pirfenidone; 3-BPFD; Pirfenidone 3-Bromo Derivative
EINECS	Contact for details

Quality Control

Our 3-Bromo Pirfenidone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.