Description

Atx Inhibitor 1 CAS NO 2225892-70-4 is a high-purity, small molecule compound designed for targeted biochemical research and development. This product serves as a potent and selective inhibitor of the Ataxia Telangiectasia and Rad3-related (ATR) kinase, a critical enzyme in the DNA damage response pathway. It is an essential research tool for oncology, pharmacology, and molecular biology laboratories investigating cancer therapeutics, DNA repair mechanisms, and cell cycle regulation.

Application

• Oncology Research: Used as a key chemical probe to study the ATR signaling pathway and its role in tumor cell survival and proliferation.
• Drug Discovery & Development: Serves as a reference standard and a lead compound in the development of novel chemotherapeutic agents targeting DNA damage repair.
• Biochemical Assays: Employed in in vitro kinase inhibition studies to determine IC50 values and assess compound potency and selectivity.
• Cell Biology Studies: Utilized in cell-based models to investigate the effects of ATR inhibition on cell cycle arrest, apoptosis, and sensitization to DNA-damaging agents.
• Academic & Pharmaceutical R&D: A critical reagent for basic scientific research and preclinical studies in academic institutions and pharmaceutical companies.

Basic Information

Product Name	Atx Inhibitor 1
CAS No.	2225892-70-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ATR Inhibitor 1; ATR Kinase Inhibitor; ATRi; DNA Damage Response Inhibitor; (Research Code/Number); (IUPAC Name - Contact for details)
EINECS	Contact for details

Quality Control

Our Atx Inhibitor 1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/LC-MS for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and other critical parameters is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.