Description

Bibf 1202 is a high-purity, small molecule compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a potent and selective kinase inhibitor, targeting specific pathways critical for cellular signaling. This makes it an essential research-grade chemical for scientists in the life sciences sector, particularly those focused on oncology, immunology, and inflammatory disease research. Global procurement teams seek this material for its critical role in preclinical studies and drug discovery pipelines.

Application

• Pharmaceutical R&D: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutic agents.
• Kinase Inhibition Studies: Used extensively in biochemical and cellular assays to study the function of specific kinase targets and validate drug mechanisms of action.
• Preclinical Research: Employed in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and toxicology profiles of potential drug candidates.
• Chemical Biology: A valuable tool compound for probing signal transduction pathways and understanding disease biology at a molecular level.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related substances.

Basic Information

Product Name	Bibf 1202
CAS No.	894783-71-2
Molecular Formula	C23H27N5O3
Molecular Weight	421.50 g/mol
Synonyms	Nintedanib; BIBF 1120; Intedanib; Vargatef; 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester; (3Z)-3-[[4-[Methyl[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]amino]-3-(2-oxo-2,3-dihydro-1H-indol-6-yl)prop-2-enoic acid methyl ester; BIBF-1202; BIBF 1202.
EINECS	Contact for details

Quality Control

Our Bibf 1202 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Keep the container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	Yellow to light brown solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.