Description

1-Fluoro-2-Methyl-3-(Trifluoromethyl)Benzene is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of fluorine and methyl substituents, which allows for precise tuning of electronic and steric properties in target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving charge transport and device efficiency.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart desirable properties such as chemical resistance, thermal stability, and altered surface energy.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Fluorine Chemistry Research: An important reagent for studying structure-activity relationships (SAR) and the effects of fluorine substitution in academic and industrial R&D settings.

Basic Information

Product Name	1-Fluoro-2-Methyl-3-(Trifluoromethyl)Benzene
CAS No.	910911-43-2
Molecular Formula	C8H6F4
Molecular Weight	178.13 g/mol
Synonyms	2-Fluoro-6-methylbenzotrifluoride; 3-(Trifluoromethyl)-2-fluorotoluene; 2-Methyl-3-(trifluoromethyl)fluorobenzene; 1-Fluoro-2-methyl-3-(trifluoromethyl)benzene; 2-Fluoro-α,α,α-trifluoro-6-methyltoluene; 2-Fluoro-6-(trifluoromethyl)toluene; 3-Trifluoromethyl-2-fluorotoluene; Benzene, 1-fluoro-2-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-Fluoro-2-Methyl-3-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Refractive Index	1.420 - 1.430
Density	1.30 - 1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.