Description

2-(4-Trifluoromethyl-Pyridin-3-Yl)-Ethylamine is a high-value pyridine-based amine building block featuring a trifluoromethyl substituent. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, leveraging the bioactivity-enhancing properties of the trifluoromethylpyridine moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to develop molecular probes and fluorescent tags for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up services for clients in life sciences.

Basic Information

Product Name	2-(4-Trifluoromethyl-Pyridin-3-Yl)-Ethylamine
CAS No.	910386-63-9
Molecular Formula	C8H9F3N2
Molecular Weight	190.17 g/mol
Synonyms	3-(2-Aminoethyl)-4-(trifluoromethyl)pyridine; 2-[4-(Trifluoromethyl)pyridin-3-yl]ethan-1-amine; 4-Trifluoromethyl-3-pyridineethylamine; 3-Pyridineethanamine, 4-(trifluoromethyl)-; 2-(4-Trifluoromethyl-3-pyridinyl)ethylamine; 910386-63-9; 2-(4-(Trifluoromethyl)pyridin-3-yl)ethanamine
EINECS	Contact for details

Quality Control

Our 2-(4-Trifluoromethyl-Pyridin-3-Yl)-Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.