Description

2-Fluoro-6-Methylpyridine-3-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound is a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Enables the exploration of new chemical space in academic and industrial laboratories through palladium-catalyzed cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex, high-value target molecules.

Basic Information

Product Name	2-Fluoro-6-Methylpyridine-3-Boronic Acid
CAS No.	906744-85-2
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	(2-Fluoro-6-methylpyridin-3-yl)boronic acid; 3-Borono-2-fluoro-6-methylpyridine; 2-Fluoro-6-methyl-3-pyridineboronic acid; 2-Fluoro-6-methylpyridine-3-boronic acid pinacol ester (common derivative); 906744-85-2; 2-Fluoro-6-methyl-3-pyridinylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Methylpyridine-3-Boronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.