Description

2-Morpholino-5-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-value, multi-functional chemical building block characterized by its reactive sulfonyl chloride group and electron-rich morpholino substituent. This compound is essential for the synthesis of complex molecules, particularly in the development of advanced pharmaceuticals and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the life sciences sector for creating novel sulfonamide derivatives with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by incorporating the sulfonamide pharmacophore.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and functional materials.
• Chemical Biology & Proteomics: Employed as a reactive probe or labeling agent for studying protein interactions and enzyme activity.
• Organic Synthesis: A versatile reagent for introducing the sulfonyl moiety in complex multi-step synthetic routes.

Basic Information

Product Name	2-Morpholino-5-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	906352-76-9
Molecular Formula	C11H11ClF3NO3S
Molecular Weight	329.72 g/mol
Synonyms	5-(Trifluoromethyl)-2-morpholinobenzenesulfonyl chloride; 2-Morpholin-4-yl-5-(trifluoromethyl)benzenesulfonyl chloride; 4-[4-(Trifluoromethyl)-2-(chlorosulfonyl)phenyl]morpholine; Benzenesulfonyl chloride, 2-morpholino-5-(trifluoromethyl)-; 906352-76-9
EINECS	Contact for details

Quality Control

Every batch of 2-Morpholino-5-(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant methods is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.