Description

(S)-n-(1-(5-Fluoropyridin-2-Yl)Ethyl)Acetamide CAS NO 905587-17-9 is a high-purity chiral acetamide derivative featuring a fluoropyridine moiety, serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its precise stereochemistry and unique molecular architecture make it invaluable for constructing complex active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in developing advanced pesticides and herbicides where the fluoropyridine group enhances bioavailability and activity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis for producing enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and biological target identification.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial API manufacturing under GMP guidelines.
• Custom Synthesis: Foundation for bespoke chemical synthesis services for clients requiring specific fluorinated chiral molecules.

Basic Information

Product Name	(S)-n-(1-(5-Fluoropyridin-2-Yl)Ethyl)Acetamide
CAS No.	905587-17-9
Molecular Formula	C9H11FN2O
Molecular Weight	182.20 g/mol
Synonyms	(S)-N-[1-(5-Fluoropyridin-2-yl)ethyl]acetamide; (S)-1-(5-Fluoropyridin-2-yl)ethylacetamide; Acetamide, N-[(1S)-1-(5-fluoro-2-pyridinyl)ethyl]-; (S)-N-(1-(5-Fluoro-2-pyridyl)ethyl)acetamide; (S)-N-(α-Methyl-5-fluoropyrid-2-ylmethyl)acetamide; 905587-17-9; (S)-enantiomer of N-(1-(5-Fluoropyridin-2-yl)ethyl)acetamide
EINECS	Contact for details

Quality Control

Our (S)-n-(1-(5-Fluoropyridin-2-Yl)Ethyl)Acetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material suitable for research and development under non-GMP or GMP conditions upon request. Certificates of Analysis (COA) are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.