Description

(S)-tert-Butyl 1-(5-Fluoropyridin-2-Yl)Ethylcarbamate is a high-purity chiral building block and advanced pharmaceutical intermediate of significant commercial importance. Its core value lies in its role as a key synthon for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) with high efficacy and safety profiles. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries, particularly those focused on innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Active Pharmaceutical Ingredient (API) Development: Used in the construction of complex molecular scaffolds for potential APIs requiring a specific (S)-configured stereocenter.
• Agrochemical Synthesis: Serves as a building block for developing advanced, enantiomerically pure agrochemicals with improved activity and environmental profiles.
• Asymmetric Catalysis & Process Chemistry: Employed in method development and scale-up processes for the production of enantiomerically enriched compounds.
• Custom Synthesis & Contract Manufacturing: A key material for custom synthesis organizations (CSOs) and CDMOs serving the global life sciences market.
• Academic & Industrial R&D: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	(S)-tert-Butyl 1-(5-Fluoropyridin-2-Yl)Ethylcarbamate
CAS No.	905587-16-8
Molecular Formula	C12H17FN2O2
Molecular Weight	240.28 g/mol
Synonyms	(S)-1-(5-Fluoropyridin-2-yl)ethyl carbamic acid tert-butyl ester; tert-Butyl N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]carbamate; (S)-tert-Butyl (1-(5-fluoropyridin-2-yl)ethyl)carbamate; Boc-(S)-1-(5-Fluoro-2-pyridyl)ethylamine; (S)-Boc-Amino(5-fluoro-2-pyridyl)ethane; (S)-N-Boc-1-(5-Fluoropyridin-2-yl)ethylamine; (S)-1-(5-Fluoro-2-pyridinyl)ethyl carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 1-(5-Fluoropyridin-2-Yl)Ethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.