Description

(6-(Trifluoromethyl)Pyridine-2,3-Diyl)Dimethanol is a high-value, multi-functional organic building block characterized by its pyridine core and dual hydroxymethyl groups. This compound matters for its versatility in synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors where the trifluoromethyl group is prized for its ability to modulate lipophilicity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitors and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity-enhancing properties of the trifluoromethylpyridine moiety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral and achiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its rigid aromatic structure and modifiable alcohol groups.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags or molecular probes for biochemical research.

Basic Information

Product Name	(6-(Trifluoromethyl)Pyridine-2,3-Diyl)Dimethanol
CAS No.	905273-57-6
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	2,3-Bis(hydroxymethyl)-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2,3-pyridinedimethanol; 2,3-Pyridinedimethanol, 6-(trifluoromethyl)-; (6-Trifluoromethyl-pyridine-2,3-diyl)-dimethanol; α,α,α-Trifluoro-2,3-pyridinedimethanol-6-methyl; 6-(Trifluoromethyl)-2,3-bis(hydroxymethyl)pyridine
EINECS	Contact for details

Quality Control

Our (6-(Trifluoromethyl)Pyridine-2,3-Diyl)Dimethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.