Description

2-Fluoro-3-Methylpyridine-5-Boronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated pyridine-based drug candidates, including kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides where the fluorinated pyridine moiety enhances biological activity and environmental stability.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Diagnostics: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes and sensors.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Fluoro-3-Methylpyridine-5-Boronic Acid
CAS No.	904326-92-7
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	(2-Fluoro-3-methylpyridin-5-yl)boronic acid; 5-Borono-2-fluoro-3-methylpyridine; 3-Methyl-2-fluoropyridine-5-boronic acid; 2-Fluoro-3-methyl-5-pyridineboronic acid; 904326-92-7; 2-Fluoro-3-methylpyridine-5-boronic acid pinacol ester (common derivative); 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluoro-3-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Methylpyridine-5-Boronic Acid is produced and tested under a strict quality management system. We guarantee high purity and consistency, with comprehensive analysis performed via HPLC, NMR, and MS to confirm identity and assay. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.