Description

1-[2-(2-Fluorophenyl)Ethyl]-2,5-Dihydro-1H-Pyrrole-2,5-Dione is a high-purity, fluorinated pyrrolidine-2,5-dione derivative, a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a fluorinated aromatic moiety with a reactive maleimide-like core, enabling precise modifications for creating novel compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on medicinal chemistry, drug discovery, and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Building Block: Used to introduce the fluorophenyl-pyrrolidinedione pharmacophore into lead compounds to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or insecticides, leveraging the fluorine atom for enhanced activity.
• Chemical Biology Probe Development: Utilized in creating activity-based probes or covalent inhibitors due to the reactivity of the dihydro-pyrrole-2,5-dione (maleimide) moiety.
• Material Science Research: Potential monomer or cross-linking agent for developing specialty polymers with unique thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	1-[2-(2-Fluorophenyl)Ethyl]-2,5-Dihydro-1H-Pyrrole-2,5-Dione
CAS No.	904315-54-4
Molecular Formula	C₁₂H₁₀FNO₂
Molecular Weight	219.21 g/mol
Synonyms	2-(2-Fluorophenyl)ethylmaleimide; 1-[2-(2-Fluorophenyl)ethyl]-1H-pyrrole-2,5-dione; N-[2-(2-Fluorophenyl)ethyl]maleimide; 2-(2-Fluorobenzyl)succinimide derivative; 904315-54-4; Fluorophenyl ethyl maleimide; FEEM
EINECS	Contact for details

Quality Control

Every batch of 1-[2-(2-Fluorophenyl)Ethyl]-2,5-Dihydro-1H-Pyrrole-2,5-Dione is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development chemicals. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.