Description

Trpc6-In-1 is a potent and selective small molecule inhibitor of the Transient Receptor Potential Canonical 6 (TRPC6) channel. This compound is a critical research tool for investigating calcium signaling pathways and their role in various physiological and pathological processes. It is primarily utilized by researchers and scientists in the fields of academic research, pharmaceutical R&D, and biotechnology for target validation and mechanistic studies.

Application

• Biomedical Research: Fundamental research on TRPC6 channel function, structure, and pharmacology.
• Cardiovascular Disease Studies: Investigation of TRPC6's role in cardiac hypertrophy, pulmonary hypertension, and renal function.
• Neurological Disorder Research: Exploration of TRPC6 channels in neuroprotection, neuronal development, and conditions like stroke and Alzheimer's disease.
• Drug Discovery & Development: Used as a reference compound or pharmacological tool in high-throughput screening (HTS) and lead optimization campaigns targeting TRPC6.
• Cell Signaling Pathway Analysis: Study of calcium-dependent signaling cascades in various cell types and disease models.

Basic Information

Product Name	Trpc6-In-1
CAS No.	901715-05-7
Molecular Formula	C₂₀H₂₀N₄O₃
Molecular Weight	364.40 g/mol
Synonyms	TRPC6-IN-1; 2-(3,4-Dimethoxyphenyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide; 901715-05-7; TRPC6 inhibitor; TRPC6 channel blocker; 2-(3,4-Dimethoxyphenyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
EINECS	Contact for details

Quality Control

Our Trpc6-In-1 is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing all quality parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.