Description

2-Chloro-5-Methylbenzene-1-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key synthetic intermediate in advanced organic synthesis. Its value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group to construct complex molecules with precision. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a critical building block for developing active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the sulfonyl moiety imparts specific biological activity.
• Dyestuff and Pigment Manufacturing: Serves as an intermediate for creating sulfonated dyes and organic pigments with enhanced properties.
• Polymer Chemistry: Employed in the modification of polymers and as a monomer or cross-linking agent for specialty polymers.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands and organocatalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2-Chloro-5-Methylbenzene-1-Sulfonyl Chloride
CAS No.	99876-69-4
Molecular Formula	C7H6Cl2O2S
Molecular Weight	225.09 g/mol
Synonyms	4-Chloro-3-methylbenzenesulfonyl chloride; 3-Methyl-4-chlorobenzenesulfonyl chloride; 2-Chloro-5-methylbenzenesulfonyl chloride; 4-Chloro-m-toluenesulfonyl chloride; 1-Chloro-2-methyl-5-sulfonyl chloride benzene; 5-Chloro-4-methylbenzenesulfonyl chloride; 2-Methyl-5-chlorobenzenesulfonyl chloride; p-Chloro-m-toluenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methylbenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC/HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.