Description

2,6-Dimethylellipticine is a synthetic derivative of the ellipticine alkaloid, a compound class known for its significant biological activity. This product is valued as a key pharmaceutical intermediate and a potent topoisomerase II inhibitor in research applications. It is primarily utilized by pharmaceutical R&D organizations and academic research institutions for the development of novel anticancer agents and biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced therapeutic compounds, particularly in oncology drug discovery pipelines.
• Biochemical Research: Used as a reference standard and active agent in studies investigating DNA intercalation and topoisomerase II inhibition mechanisms.
• Anticancer Agent Development: Acts as a core scaffold for the design and synthesis of new ellipticine analogs with optimized efficacy and reduced toxicity profiles.
• In Vitro & In Vivo Studies: Employed in preclinical research to evaluate antitumor activity, pharmacokinetics, and cellular apoptosis pathways.
• Reference Material: Provides a high-purity standard for analytical method development, validation, and quality control in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	2,6-Dimethylellipticine
CAS No.	99759-40-7
Molecular Formula	C20H18N2
Molecular Weight	286.37 g/mol
Synonyms	2,6-Dimethyl-6H-pyrido[4,3-b]carbazole; 9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole; 2,6-Dimethyl-ellipticine; NSC 338710; Ellipticine, 2,6-dimethyl-; 5,11-Dimethyl-9-methoxy-6H-pyrido[4,3-b]carbazole
EINECS	Contact for details

Quality Control

Our 2,6-Dimethylellipticine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to ensure long-term stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.