Description

5-Bromo-2-Fluoro-m-Xylene is a halogenated aromatic compound of significant interest in advanced organic synthesis. Its value lies in its role as a versatile and reactive building block, particularly for introducing bromo and fluoro substituents into complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings.
• Material Science Research: Building block for synthesizing novel organic electronic materials, liquid crystals, or polymers with specific optoelectronic properties.
• Fluorinated Compound Library: Essential for medicinal chemistry programs focused on constructing diverse libraries of fluorinated compounds for high-throughput screening.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring precise halogenation.

Basic Information

Product Name	5-Bromo-2-Fluoro-m-Xylene
CAS No.	99725-44-7
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	1-Bromo-3,5-dimethyl-4-fluorobenzene; 4-Bromo-2,6-dimethylfluorobenzene; 2-Fluoro-5-bromo-m-xylene; 5-Bromo-2-fluoro-1,3-dimethylbenzene; m-Xylene, 5-bromo-2-fluoro-; 4-Fluoro-3,5-dimethylbromobenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-m-Xylene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.