Description

Zacopride Hydrochloride [Usan:Inn] CAS NO 99617-34-2 is a high-purity, pharmacologically active compound belonging to the benzamide class, recognized for its potent and selective antagonistic activity at the 5-HT3 receptor. This makes it a critical reference standard and active pharmaceutical ingredient (API) for advanced research and development in neuropharmacology and gastroenterology. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and academic institutions engaged in the study of serotonin pathways, emesis control, and gastrointestinal motility disorders.

Application

• Pharmaceutical Reference Standard: Serves as a primary chemical standard for analytical method development, validation, and quality control (QC) testing of related drug substances and products.
• Neuroscience Research: A key tool for in vitro and in vivo studies investigating the role of 5-HT3 receptors in central nervous system functions, including anxiety, cognition, and reward pathways.
• Gastrointestinal Drug Development: Used in preclinical research for developing novel therapeutics aimed at treating conditions like chemotherapy-induced nausea and vomiting (CINV) and irritable bowel syndrome (IBS).
• Biochemical Assays: Employed in receptor binding assays and functional studies to screen and characterize new chemical entities targeting serotonin receptors.
• Academic & Clinical Research: Supports fundamental pharmacological research in university and hospital settings, facilitating a deeper understanding of serotonergic mechanisms.

Basic Information

Product Name	Zacopride Hydrochloride [Usan:Inn] CAS NO 99617-34-2
CAS No.	99617-34-2
Molecular Formula	C20H28N4O3·HCl
Molecular Weight	424.93 g/mol
Synonyms	Zacopride HCl; Zacopride Hydrochloride; 4-Amino-N-(1-azabicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxybenzamide Hydrochloride; AH-11110A; Zacoprida [Spanish]; Zacopridum [Latin]; UNII-2S7998S4F1
EINECS	Contact for details

Quality Control

Our Zacopride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and control of related substances and residual solvents. Certificates of Analysis (COA) detailing all test results against established specifications are available upon request to ensure full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤2.0%; Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.