Description

Dexloxiglumide CAS NO 119817-90-2 is a selective and potent cholecystokinin A (CCK-A) receptor antagonist. This compound is of significant interest in pharmaceutical research and development due to its potential to modulate gastrointestinal motility and pancreatic secretion. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical industry, particularly those developing treatments for gastrointestinal disorders and related conditions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced drug candidates targeting the CCK-A receptor pathway.
• Biochemical Research: Used as a selective pharmacological tool to study cholecystokinin receptor function and signaling in vitro and in vivo.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Drug Discovery & Development: Employed in preclinical studies to investigate potential therapies for conditions like irritable bowel syndrome (IBS), pancreatitis, and satiety regulation.
• Academic Research: Utilized in university and institutional labs for fundamental research on gastrointestinal physiology and receptor pharmacology.

Basic Information

Product Name	Dexloxiglumide
CAS No.	119817-90-2
Molecular Formula	C26H33N3O6
Molecular Weight	483.56 g/mol
Synonyms	(R)-4-[[3,4-Dichlorobenzoyl)amino]-5-[(3-methoxypropyl)pentylamino]-5-oxopentanoic acid; Dexloxiglumide; (R)-Loxiglumide; CR 2194; CR-2194; R-Loxiglumide; (R)-4-[[(3,4-Dichlorophenyl)carbonyl]amino]-5-[(3-methoxypropyl)pentylamino]-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Our Dexloxiglumide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA), which includes results from advanced techniques such as HPLC, NMR, and mass spectrometry. Specifications are designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.