Description

Cilansetron CAS NO 120635-47-4 is a selective serotonin 5-HT3 receptor antagonist. This compound is of significant interest in pharmaceutical research and development due to its targeted mechanism of action. It is primarily utilized by researchers and manufacturers in the pharmaceutical industry for the development of therapeutic agents.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of new therapeutic compounds.
• Gastrointestinal Disorder Research: Investigated for its potential application in treating conditions like irritable bowel syndrome (IBS) and chemotherapy-induced nausea and vomiting.
• Neuropharmacology Studies: Used in preclinical and clinical research to study the role of 5-HT3 receptors in the central and peripheral nervous systems.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Chemical Synthesis: Acts as a sophisticated building block for the synthesis of more complex molecules in medicinal chemistry.

Basic Information

Product Name	Cilansetron
CAS No.	120635-47-4
Molecular Formula	C20H24N4O2
Molecular Weight	352.43 g/mol
Synonyms	KC 9946; Cilansetronum; (3R)-3-[(1-Methyl-1H-indol-3-yl)carbonyl]amino]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-one; 5-HT3 Receptor Antagonist KC 9946; UNII-6R3K5QWG8C
EINECS	Contact for details

Quality Control

Our Cilansetron is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR to ensure it meets high-grade standards for research use. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.