Description

Loxiglumide is a potent and selective cholecystokinin A (CCK-A) receptor antagonist. This compound is a critical research tool for investigating gastrointestinal physiology and the role of CCK in appetite regulation and pancreatic secretion. It is primarily utilized by pharmaceutical R&D teams and academic researchers in the fields of gastroenterology and metabolic disorders. Loxiglumide CAS NO 107097-80-3 represents a high-purity standard for reliable and reproducible experimental results.

Application

• Pharmacological Research: A key reference standard for studying cholecystokinin (CCK) receptor subtypes, their distribution, and signaling pathways.
• Gastrointestinal Physiology Studies: Used to investigate the role of CCK in pancreatic enzyme secretion, gallbladder contraction, and gastric emptying.
• Metabolic Disorder Research: Employed in preclinical models to explore the potential of CCK-A receptor antagonism in modulating satiety and food intake.
• Drug Discovery & Development: Serves as a lead compound or benchmark for developing novel therapeutic agents targeting CCK receptors for conditions like pancreatitis, IBS, or obesity.
• Biochemical Assay Development: Used as a ligand in receptor binding assays and functional tests to screen for new receptor modulators.
• Academic & Clinical Research: Supports fundamental and translational research in university and hospital laboratories worldwide.

Basic Information

Product Name	Loxiglumide
CAS No.	107097-80-3
Molecular Formula	C₂₉H₃₅ClN₄O₇
Molecular Weight	575.06 g/mol
Synonyms	CR 1505; CR-1505; Loxiglumide (CR1505); 4-(3,4-Dichlorobenzoylamino)-5-(dipentylamino)-5-oxopentanoic Acid; (R,S)-4-(3,4-Dichlorobenzamido)-N-(dipentylcarbamoyl)-5-aminopentanoic Acid
EINECS	Contact for details

Quality Control

Our Loxiglumide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Our quality commitment supports your need for reliable and consistent biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at 2-8°C. The compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.