Description

Cilansetron CAS NO 120635-74-7 is a selective serotonin 5-HT3 receptor antagonist. This compound is of significant interest in pharmaceutical research and development due to its targeted mechanism of action. It is primarily utilized by researchers and manufacturers in the pharmaceutical industry for the development of therapeutic agents.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of new therapeutic compounds targeting the 5-HT3 receptor pathway.
• Preclinical Studies: Used in laboratory research to investigate the pharmacological effects, efficacy, and safety profiles of 5-HT3 receptor antagonists in various biological models.
• Chemical Synthesis: Acts as a critical building block for medicinal chemists in the synthesis of novel analogs and derivatives for structure-activity relationship (SAR) studies.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Academic Research: Utilized in university and institutional settings for fundamental studies in neuropharmacology and gastroenterology.

Basic Information

Product Name	Cilansetron
CAS No.	120635-74-7
Molecular Formula	C20H24N4O3
Molecular Weight	368.43 g/mol
Synonyms	KC 9946; Cilansetronum; (3R)-3-[(1-Methyl-1H-indol-3-yl)carbonyl]amino]-2-(1-piperazinyl)-5,6,7,8-tetrahydro-1H-cyclohepta[b]pyrrol-4-one; UNII-1N2V6E2J9Q
EINECS	Contact for details

Quality Control

Our Cilansetron is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR to ensure it meets high-grade standards. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to guarantee traceability and consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.