Description

Mosapride Citrate is a high-purity pharmaceutical active ingredient, a selective 5-HT4 receptor agonist used as a potent gastrointestinal prokinetic agent. It is critical for the formulation of medications designed to treat functional dyspepsia, gastroesophageal reflux disease (GERD), and other gastrointestinal motility disorders. This compound is essential for pharmaceutical manufacturers and research institutions developing next-generation treatments for digestive system ailments.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of prescription medications for gastrointestinal disorders.
• Gastroprokinetic Drug Development: Key component in R&D for drugs targeting impaired gastric motility and delayed gastric emptying.
• Treatment of Functional Dyspepsia: Used in drugs alleviating symptoms like postprandial fullness, early satiation, and epigastric pain.
• GERD (Gastroesophageal Reflux Disease) Therapy: Incorporated into formulations to reduce reflux symptoms and improve esophageal clearance.
• Veterinary Pharmaceutical Applications: Potential use in developing prokinetic treatments for companion animals.
• Reference Standard: Serves as an analytical standard in quality control laboratories for drug testing and method validation.
• Clinical Research: Utilized in preclinical and clinical studies investigating gastrointestinal pharmacology.

Basic Information

Product Name	Mosapride Citrate
CAS No.	112885-42-4
Molecular Formula	C21H25ClFN3O3 • C6H8O7
Molecular Weight	650.04 g/mol
Synonyms	4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide citrate; Mosapride Citrate Dihydrate; AS-4370; Gasmotin (brand name); GM-611 (citrate); 1-Morpholin-4-yl-4-(4-fluorobenzyl)piperazin-2-ylmethyl 5-chloro-2-ethoxy-4-aminobenzoat citrate
EINECS	Contact for details

Quality Control

Our Mosapride Citrate is manufactured under strict quality management systems, targeting purity levels suitable for pharmaceutical applications. Each batch undergoes comprehensive analytical testing including HPLC for assay and impurity profiling, residual solvent analysis, and identification tests. A Certificate of Analysis (COA) is provided with each shipment, detailing compliance with agreed specifications. We support development and commercial projects requiring standards aligned with ICH guidelines and current Good Manufacturing Practice (cGMP) principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.