Description

11-Ketotetranorprostaglandin F2Alpha is a key prostaglandin metabolite and synthetic intermediate. This compound is significant for its role as a biomarker in clinical research and as a high-purity building block in advanced pharmaceutical synthesis. It is primarily required by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in the development of therapeutics related to inflammation, renal function, and metabolic pathways.

Application

• Biomarker Standard: Used as a certified reference material (CRM) for the quantitative analysis of prostaglandin metabolites in biological fluids for clinical and research purposes.
• Pharmaceutical Intermediate: Serves as a critical synthetic precursor in the production of specialized prostaglandin analogs and related bioactive compounds.
• Metabolic Pathway Research: Employed in biochemical studies to investigate the arachidonic acid cascade, inflammation mechanisms, and renal eicosanoid activity.
• Diagnostic Kit Development: Integrated into ELISA and LC-MS/MS assay kits for the accurate measurement of physiological and pathological states.
• Quality Control Reagent: Acts as an internal standard in analytical laboratories to ensure the accuracy and precision of prostaglandin metabolite testing.

Basic Information

Product Name	11-Ketotetranorprostaglandin F2Alpha
CAS No.	99570-16-8
Molecular Formula	C16H26O5
Molecular Weight	298.38 g/mol
Synonyms	11-Keto-tetranor-PGF2α; 9α,11α-Dihydroxy-15-oxo-2,3,4,5-tetranorprostanoic Acid; 11-Ketotetranor PGF2 alpha; PGF2α Tetranor Metabolite; 15-Oxo-9,11-dihydroxy-2,3,4,5-tetranorprostanoic Acid; 11-Keto-tetranor-prostaglandin F2α; Tetranor PGKM; 9,11-Dihydroxy-15-oxo-2,3,4,5-tetranorprostan-1-oic Acid
EINECS	Contact for details

Quality Control

Our 11-Ketotetranorprostaglandin F2Alpha is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.