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6-Deoxy-6-Fluorocyclomaltoheptaose CAS NO 99552-37-1


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CAS No.:99552-37-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Deoxy-6-Fluorocyclomaltoheptaose is a strategically fluorinated derivative of β-cyclodextrin, a well-known host molecule in supramolecular chemistry. This modification introduces a fluorine atom at the C-6 position, significantly altering the cavity's electron density and host-guest interaction properties compared to the native compound. It is a critical research chemical for scientists in pharmaceutical development, analytical chemistry, and material science who require precise molecular recognition and separation capabilities. The compound enables advanced studies in chiral separation, drug delivery systems, and the creation of novel sensor materials.

Application

  • Chiral Stationary Phases (CSPs): A key selector for High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) to separate enantiomers of pharmaceutical intermediates and active ingredients.
  • Pharmaceutical Research: Used as a complexing agent to study and improve the solubility, stability, and bioavailability of poorly soluble drug candidates.
  • Chemical Sensing: Serves as a recognition element in the design of fluorogenic or electrochemical sensors for specific analytes.
  • Catalysis: Acts as a ligand or co-catalyst in asymmetric synthesis, leveraging its chiral environment to influence reaction stereoselectivity.
  • Material Science: Incorporated into polymers or surfaces to create selective membranes for filtration or molecular imprinting technologies.
  • Reference Standard: Used as an analytical standard in quality control and method development for cyclodextrin-based products and processes.

Basic Information

Product Name 6-Deoxy-6-Fluorocyclomaltoheptaose
CAS No. 99552-37-1
Molecular Formula C42H69FO34
Molecular Weight 1161.00 g/mol
Synonyms 6-Deoxy-6-fluoro-β-cyclodextrin; 6-Fluoro-6-deoxy-β-cyclodextrin; 6-Fluoro-β-cyclodextrin; 6-F-β-CD; 6-Monofluoro-β-cyclodextrin; β-Cyclodextrin, 6-deoxy-6-fluoro-; Heptakis(6-deoxy-6-fluoro)-β-cyclodextrin (fully substituted analog)
EINECS Contact for details

Quality Control

Our 6-Deoxy-6-Fluorocyclomaltoheptaose is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Specifications are aligned with research-grade standards, and a comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), water content, and specific rotation is provided with every shipment to support your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect purity and stability. Handle with appropriate personal protective equipment in a well-ventilated laboratory setting.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Specific Rotation Contact for details
Fluorine Content Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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