Description

3A-Amino-3A-Deoxy-(2As,3As)-α-Cyclodextrin Hydrate is a chemically modified derivative of α-cyclodextrin, featuring a single primary amino group at the 3-position of one glucose unit. This specific functionalization is crucial as it introduces a reactive handle for further chemical conjugation, significantly enhancing the molecule's utility in creating targeted host-guest complexes. It is primarily sought after by researchers and manufacturers in the pharmaceutical and biotechnology sectors for advanced applications in drug delivery, chiral separation, and molecular sensing. The compound's ability to form inclusion complexes with various guest molecules is leveraged to improve solubility, stability, and bioavailability of active ingredients.

Application

• Pharmaceutical Drug Delivery: Acts as a functionalized carrier to improve the solubility, stability, and targeted release of poorly water-soluble active pharmaceutical ingredients (APIs).
• Chiral Separation & Analysis: Serves as a chiral selector or stationary phase modifier in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for enantiomeric resolution.
• Molecular Sensing & Diagnostics: Used as a building block for constructing chemosensors and biosensors, where the amino group allows attachment of signaling moieties.
• Catalysis: Functions as a ligand or scaffold for asymmetric catalysts in synthetic organic chemistry.
• Bioconjugation & Protein Modification: The primary amino group enables covalent coupling to proteins, peptides, or other biomolecules for creating novel conjugates.
• Material Science: Incorporated into polymers, gels, or nanomaterials to impart host-guest properties for smart materials and controlled release systems.

Basic Information

Product Name	3A-Amino-3A-Deoxy-(2As,3As)-α-Cyclodextrin Hydrate
CAS No.	121916-94-7
Molecular Formula	C36H61NO30 · xH2O
Molecular Weight	Approx. 995.86 (Anhydrous basis)
Synonyms	Mono-6A-amino-6A-deoxy-α-cyclodextrin; 6A-Amino-6A-deoxy-α-cyclodextrin; 6-Monoamino-6-monodeoxy-α-cyclodextrin; 3A-Amino-3A-deoxy-α-cyclodextrin; Amino-α-CD; α-Cyclodextrin, 3A-amino-3A-deoxy-; 3A-Azido-3A-deoxy-(2AS,3AS)-α-cyclodextrin (precursor)
EINECS	Contact for details

Quality Control

Our 3A-Amino-3A-Deoxy-(2As,3As)-α-Cyclodextrin Hydrate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Specifications are aligned with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing results for assay, impurity profile, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. Due to its hygroscopic nature, the container should be kept sealed in a desiccated environment to prevent moisture uptake. Handle the material under an inert atmosphere if prolonged exposure is anticipated during weighing.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 10.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.