Description

6-o-α-Maltosyl-β-Cyclodextrin Hydrate is a chemically modified cyclodextrin derivative, where a maltosyl unit is enzymatically attached to the primary hydroxyl side of the β-cyclodextrin ring. This modification significantly enhances its solubility and complexation capabilities compared to native β-cyclodextrin, making it a superior molecular encapsulation agent. It is primarily utilized in the pharmaceutical, food, and cosmetic industries to improve the solubility, stability, and bioavailability of active ingredients. This advanced excipient is critical for formulators seeking to overcome challenges with poorly soluble compounds.

Application

• Pharmaceutical Solubility Enhancement: Used as an advanced excipient to dramatically increase the aqueous solubility and dissolution rate of poorly soluble active pharmaceutical ingredients (APIs).
• Stabilization of Sensitive Compounds: Protects labile molecules (e.g., vitamins, flavors, pigments) from oxidation, light degradation, and hydrolysis by forming inclusion complexes.
• Taste and Odor Masking: Effectively encapsulates bitter or unpleasant-tasting compounds in oral drug formulations and functional food products.
• Controlled Release Systems: Serves as a component in drug delivery matrices to modulate the release profile of encapsulated actives.
• Analytical Chemistry: Employed as a chiral selector in capillary electrophoresis and HPLC for the separation of enantiomers.
• Cosmetic Formulations: Enhances the stability and skin penetration of active ingredients in creams, lotions, and serums.
• Food & Nutraceuticals: Used to stabilize sensitive nutrients, flavors, and colors in fortified foods and dietary supplements.

Basic Information

Product Name	6-o-α-Maltosyl-β-Cyclodextrin Hydrate
CAS No.	104723-60-6
Molecular Formula	C54H92O46 · xH2O
Molecular Weight	Anhydrous: ~1333.29 g/mol (hydrate form variable)
Synonyms	6-O-α-Maltosyl-β-cyclodextrin; G2-β-CD; Maltosyl-β-cyclodextrin; 6-Maltosyl-β-cyclodextrin; 6-O-(4-O-α-D-Glucopyranosyl-α-D-glucopyranosyl)-β-cyclodextrin; β-Cyclodextrin Maltosyl Ether; 6-O-α-D-Maltosyl-β-cyclodextrin; 6A-O-α-Maltosyl-β-cyclodextrin Hydrate
EINECS	Contact for details

Quality Control

Our 6-o-α-Maltosyl-β-Cyclodextrin Hydrate is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and compliance with relevant standards for pharmaceutical and food-grade applications. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as assay, water content, residue on ignition, and microbiological quality. We can support compliance with GMP, ICH Q7 guidelines, and FCC requirements as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). To prevent caking and decomposition, the container must be kept tightly sealed in a low-humidity environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 10.0% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	+160° to +170° (c=1 in H2O)
Microbiological Quality	Total Aerobic Microbial Count ≤ 1000 cfu/g; Total Combined Yeasts/Molds ≤ 100 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.