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3A-Amino-3A-Deoxy-(2As,3As)-β-Cyclodextrin CAS NO 117194-77-1
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CAS No.:117194-77-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3A-Amino-3A-Deoxy-(2As,3As)-β-Cyclodextrin is a chemically modified derivative of β-cyclodextrin, featuring a primary amino group at the 3-position of one glucose unit. This functionalization is critical as it introduces a reactive site for covalent conjugation, significantly enhancing the molecule's ability to form stable inclusion complexes with a wide range of guest molecules. It is an essential advanced intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require precise molecular encapsulation, chiral separation, or targeted drug delivery systems.
Application
- Pharmaceutical Drug Delivery: Serves as a functionalized carrier for enhancing the solubility, stability, and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs).
- Chiral Separation & Analysis: Used as a chiral selector or stationary phase modifier in High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) for the resolution of enantiomers.
- Bioconjugation & Sensor Development: The primary amino group enables covalent attachment to proteins, enzymes, or fluorescent probes for creating biosensors and diagnostic assays.
- Catalysis: Acts as a supramolecular host in catalytic systems to improve reaction selectivity and efficiency by encapsulating catalysts or substrates.
- Cosmetic & Personal Care Formulations: Employed to stabilize fragrances, vitamins, and other sensitive ingredients in creams and lotions.
- Food & Flavor Technology: Used to mask unpleasant tastes, protect flavors from oxidation, and control the release of aroma compounds.
Basic Information
| Product Name | 3A-Amino-3A-Deoxy-(2As,3As)-β-Cyclodextrin |
| CAS No. | 117194-77-1 |
| Molecular Formula | C42H71NO34 |
| Molecular Weight | 1134.00 g/mol (approx.) |
| Synonyms | 3A-Amino-3A-deoxy-β-cyclodextrin; 3-Amino-3-deoxy-β-cyclodextrin; 3A-Amino-β-cyclodextrin; 3-Deoxy-3-amino-β-cyclodextrin; Mono(3A-amino-3A-deoxy)-β-cyclodextrin; 3-NH2-β-CD; β-Cyclodextrin, 3-amino-3-deoxy-; Amino-β-CD |
| EINECS | Contact for details |
Quality Control
Our 3A-Amino-3A-Deoxy-(2As,3As)-β-Cyclodextrin is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail key parameters such as assay, impurity profile, and specific rotation. Specifications can be aligned with research-grade or development-phase requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions to maintain stability and prevent clumping.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 10.0 % |
| Specific Rotation | Contact for details |
| Residue on Ignition | ≤ 0.5 % |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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