Description

6A,6B,6C,6D,6E,6F,6G-Heptakis-o-(2-Hydroxypropyl)-β-Cyclodextrin is a chemically modified cyclodextrin derivative, specifically engineered to enhance the solubility, stability, and bioavailability of poorly soluble active ingredients. This product matters as a premier pharmaceutical excipient and complexing agent, offering superior performance over native cyclodextrins for advanced drug formulation. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to overcome formulation challenges and improve product efficacy.

Application

• Pharmaceutical Solubilization Agent: Enhances the aqueous solubility and dissolution rate of poorly water-soluble APIs for oral, injectable, and topical formulations.
• Drug Delivery & Stabilization: Forms inclusion complexes to protect sensitive active ingredients from degradation (e.g., oxidation, hydrolysis) and control release profiles.
• Taste Masking: Effectively encapsulates bitter-tasting drug molecules to improve palatability in oral suspensions, syrups, and chewable tablets.
• Agrochemical Formulations: Used to improve the stability, solubility, and efficacy of pesticides, herbicides, and plant growth regulators.
• Cosmetic & Personal Care: Acts as a carrier for fragrances, vitamins, and other active compounds in creams, lotions, and serums, enhancing skin penetration and stability.
• Analytical Chemistry: Serves as a chiral selector in capillary electrophoresis and HPLC for enantiomeric separation and analysis.
• Catalyst & Reaction Medium: Provides a unique micro-environment in organic synthesis to influence reaction selectivity and yield.

Basic Information

Product Name	6A,6B,6C,6D,6E,6F,6G-Heptakis-o-(2-Hydroxypropyl)-β-Cyclodextrin
CAS No.	107745-73-3
Molecular Formula	C63H112O35
Molecular Weight	~1541.5 g/mol
Synonyms	Hydroxypropyl-β-Cyclodextrin, HP-β-CD; 2-Hydroxypropyl-β-cyclodextrin; Heptakis(2-hydroxypropyl)-β-cyclodextrin; HPBCD; (2-Hydroxypropyl)-β-cyclodextrin; β-Cyclodextrin, 2-hydroxypropyl ether; Encapsin® HPB; Kleptose® HPB
EINECS	Contact for details

Quality Control

Our 6A,6B,6C,6D,6E,6F,6G-Heptakis-o-(2-Hydroxypropyl)-β-Cyclodextrin is manufactured under a strict quality management system. Each batch is tested to ensure it meets stringent specifications for identity, purity, and substitution degree, relevant for pharmaceutical (IP/BP/EP/NF) and high-purity industrial applications. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, residual solvents, and microbiological data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed to prevent absorption of atmospheric moisture, which can affect product performance and stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HP-β-CD)	≥ 98.0% (on dried basis)
Substitution Degree (MS)	0.6 - 0.9 (or as specified)
Water Content (KF)	≤ 5.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines
Microbiological Enumeration	Meets Ph. Eur. criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.