Description

Heptakis-(2,3-Di-o-Acetyl-6-o-Tert.-Butyldimethylsilyl)-β-Cyclodextrin is a highly functionalized derivative of β-cyclodextrin, engineered for advanced molecular encapsulation and solubility enhancement. This compound is critical for research and development in pharmaceutical chemistry, where it acts as a sophisticated host molecule to improve the stability, bioavailability, and delivery of active ingredients. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for chiral separations, catalysis, and formulation development.

Application

• Pharmaceutical Research & Development: As a chiral stationary phase additive or mobile phase modifier in High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) for the separation of enantiomers.
• Drug Formulation & Delivery: To form inclusion complexes with poorly soluble drug candidates, enhancing their aqueous solubility, dissolution rate, and chemical stability.
• Catalysis & Organic Synthesis: Serving as a molecular scaffold or protecting group in asymmetric synthesis to influence reaction stereoselectivity and regioselectivity.
• Analytical Chemistry Standards: Used as a high-purity reference standard for method development and validation in analytical laboratories.
• Agrochemical Formulations: Application in the development of advanced pesticide and herbicide formulations to improve efficacy and environmental compatibility.
• Material Science: Incorporation into sensor materials or functional polymers to create selective binding sites for specific guest molecules.

Basic Information

Product Name	Heptakis-(2,3-Di-o-Acetyl-6-o-Tert.-Butyldimethylsilyl)-β-Cyclodextrin
CAS No.	123172-94-1
Molecular Formula	C119H224O56Si7
Molecular Weight	2795.2 g/mol (approx.)
Synonyms	Heptakis(2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin; 2,3-Di-O-acetyl-6-O-TBDMS-β-cyclodextrin; Per(2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin; 6-O-TBDMS-2,3-di-OAc-β-CD; Fully Acetylated and Silylated β-Cyclodextrin; β-CD-(Ac)14-(TBDMS)7; TBDMS-peracetylated-β-cyclodextrin
EINECS	Contact for details

Quality Control

Our Heptakis-(2,3-Di-o-Acetyl-6-o-Tert.-Butyldimethylsilyl)-β-Cyclodextrin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.