Description

Cyclomaltoheptaose-1-Adamantanemethanol is a chemically modified cyclodextrin derivative, specifically a conjugate of β-cyclodextrin (cyclomaltoheptaose) and 1-adamantanemethanol. This compound is engineered to leverage the unique host-guest complexation properties of cyclodextrins with the rigid, lipophilic adamantane moiety, creating a sophisticated molecular scaffold. It is primarily utilized in advanced pharmaceutical research, analytical chemistry, and materials science for applications requiring precise molecular recognition, controlled release, or solubility enhancement. Researchers and product developers in drug delivery, supramolecular chemistry, and specialty chemical synthesis will find this a valuable tool for creating novel functional systems.

Application

• Pharmaceutical Research & Drug Delivery: Acts as a functionalized carrier for enhancing the solubility, stability, and bioavailability of poorly soluble active pharmaceutical ingredients (APIs) through host-guest inclusion complexes.
• Supramolecular Chemistry & Molecular Recognition: Serves as a key building block for constructing complex molecular assemblies, sensors, and switches due to the specific binding affinity of the adamantane group for complementary hosts like cucurbiturils.
• Analytical Chemistry & Chromatography: Used as a chiral stationary phase modifier or a selective agent in capillary electrophoresis and HPLC for the separation of enantiomers and isomers.
• Functional Materials & Nanotechnology: Incorporated into polymers, hydrogels, and surface coatings to introduce stimuli-responsive or self-assembling properties based on reversible adamantane-host interactions.
• Cosmetic & Personal Care Formulations: Employed to stabilize fragile compounds, control fragrance release, or improve the delivery of active ingredients in topical applications.
• Catalysis: Utilized to design enzyme-mimetic catalysts or to immobilize catalytic species within a cyclodextrin cavity for improved selectivity and recyclability.

Basic Information

Product Name	Cyclomaltoheptaose-1-Adamantanemethanol
CAS No.	101412-93-5
Molecular Formula	C55H88O35
Molecular Weight	1285.26 g/mol
Synonyms	1-Adamantanemethanol, β-cyclodextrin conjugate; β-Cyclodextrin-1-adamantylmethanol inclusion compound; Heptakis(6-deoxy-6-((1-adamantyl)methylthio))-β-cyclodextrin (related derivative); Adamantyl-modified β-cyclodextrin; Cyclomaltoheptaose adamantane conjugate; 1-((1-Adamantyl)methyl)-β-cyclodextrin; Host-guest complex precursor; Mono(6-deoxy-6-((1-adamantyl)methylamino))-β-cyclodextrin (possible synthetic intermediate)
EINECS	Contact for details

Quality Control

Our Cyclomaltoheptaose-1-Adamantanemethanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Standard quality control includes HPLC for assay and impurity profiling, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting compliance with agreed specifications. Custom synthesis and purification to meet specific research or cGMP guidelines are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under conditions that minimize exposure to ambient humidity and strong light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.