Description

Domperidone Maleate is a high-purity pharmaceutical active ingredient, specifically the maleate salt form of the dopamine antagonist domperidone. This compound is critical for ensuring the efficacy and stability of finished pharmaceutical formulations. It is primarily utilized by manufacturers in the pharmaceutical industry for the production of antiemetic and gastroprokinetic medications.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of prescription drugs for nausea and vomiting.
• Gastroprokinetic Formulations: Used in medications that stimulate gastric motility and treat gastroparesis.
• Antiemetic Drug Production: Key component in tablets, suspensions, and other dosage forms designed to prevent nausea.
• Veterinary Medicine: Applicable in veterinary pharmaceutical products for similar gastrointestinal indications.
• Research & Development: Serves as a reference standard and raw material in pharmacological research and new drug development.
• Generic Drug Manufacturing: Essential for producing bioequivalent generic versions of branded domperidone medications.

Basic Information

Product Name	Domperidone Maleate
CAS No.	99497-03-7
Molecular Formula	C22H24ClN5O2 • C4H4O4
Molecular Weight	542.0 g/mol
Synonyms	Domperidone Maleate Salt; 5-Chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one maleate; Domperidone hydrogen maleate; Motilium (as maleate salt); CAS 99497-03-7
EINECS	Contact for details

Quality Control

Our Domperidone Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including identity, assay, and impurity profile verification. Certificates of Analysis (COA) compliant with current industry practices are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.