Description

n-Desmethylcarboxy Terbinafine is a key pharmaceutical intermediate and metabolite of the antifungal agent terbinafine. This compound is of significant value in the research, development, and quality control of antifungal medications. It is primarily required by pharmaceutical manufacturers, analytical laboratories, and research institutions for use in reference standards, metabolite studies, and impurity profiling.

Application

• Primary reference standard for the analytical quantification of terbinafine and its metabolites.
• Critical intermediate in the research and synthesis of novel antifungal agents.
• Impurity standard for ensuring the purity and quality of commercial terbinafine API (Active Pharmaceutical Ingredient).
• Metabolite for pharmacokinetic and drug metabolism studies in pharmaceutical R&D.
• Calibrant in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) methods.
• Biochemical research tool for investigating the mechanism of action of allylamine antifungals.

Basic Information

Product Name	n-Desmethylcarboxy Terbinafine
CAS No.	99473-15-1
Molecular Formula	C20H29NO2
Molecular Weight	315.45 g/mol
Synonyms	Carboxy Terbinafine; Terbinafine Carboxylic Acid; N-Desmethyl Terbinafine Carboxylic Acid; (2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl](2-naphthalenylmethyl)amino]benzoic Acid; Terbinafine Metabolite; Terbinafine Acid Metabolite; ATF Acid; LY 248663 Acid
EINECS	Contact for details

Quality Control

Our n-Desmethylcarboxy Terbinafine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for pharmaceutical analysis and research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.