Description

n-Acetyl-13-Dihydrodaunomycin is a key synthetic intermediate and derivative of the anthracycline class of compounds. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel chemotherapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in oncology drug discovery and advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel anthracycline-based anticancer drugs and their analogs.
• Biochemical Research: Used as a reference standard or probe in studies investigating the structure-activity relationships (SAR) of daunomycin derivatives.
• Academic Research: Employed in university and institutional labs for chemical and pharmacological studies related to topoisomerase II inhibition.
• Process Development: Serves as a key intermediate for process chemists developing scalable synthetic routes for complex active pharmaceutical ingredients (APIs).
• Metabolite Studies: Potential use in the study of drug metabolism pathways for anthracycline chemotherapeutics.

Basic Information

Product Name	n-Acetyl-13-Dihydrodaunomycin
CAS No.	99296-47-6
Molecular Formula	C27H31NO11
Molecular Weight	545.54 g/mol
Synonyms	13-Acetyldaunomycinone; 13-Acetyldaunorubicinone; 13-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; 13-Acetyl-13-dihydrodaunorubicin; Daunomycinone, 13-acetyl-; 13-Acetyl-13-dihydrodaunomycin; N-Acetyl-13-dihydrodaunomycin
EINECS	Contact for details

Quality Control

Our n-Acetyl-13-Dihydrodaunomycin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.