Description

Dihomo-Prostaglandin I(2) is a stable synthetic analog of prostacyclin, a potent vasodilator and inhibitor of platelet aggregation. This compound is valued for its enhanced chemical stability and potent biological activity in research and development settings. It is primarily utilized by pharmaceutical researchers and life science companies focused on cardiovascular therapeutics, vascular biology studies, and the development of novel anti-thrombotic agents.

Application

• Pharmaceutical R&D as a reference standard or active pharmaceutical ingredient (API) intermediate for cardiovascular drugs.
• Biochemical Research for studying prostacyclin receptor (IP receptor) signaling pathways and vascular physiology.
• Cell Culture Studies to investigate the effects of prostacyclin analogs on endothelial cell function and platelet inhibition.
• Preclinical Development of novel therapeutic agents targeting thrombosis, pulmonary hypertension, and ischemia-reperfusion injury.
• Analytical Standard for quality control and method development in HPLC and LC-MS assays.

Basic Information

Product Name	Dihomo-Prostaglandin I(2)
CAS No.	99286-22-3
Molecular Formula	C23H38O5
Molecular Weight	394.55 g/mol
Synonyms	Dihomo-PGI2; 17,18,19,20-Tetranor-16-carbaprostaglandin I2; 16-Carba-17,18,19,20-tetranor-PGI2; Carbacyclin derivative; 9-Deoxy-9α,11α-epoxy-15-cyclohexyl-ω-pentanor-13,14-dihydro-16-carba-prostaglandin I2; 15-Cyclohexyl-ω-pentanor-13,14-dihydro-16-carbaprostaglandin I2
EINECS	Contact for details

Quality Control

Our Dihomo-Prostaglandin I(2) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.