Description

Griseolic Acid B CAS NO 98890-01-8 is a secondary metabolite and a potent, selective inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase. This targeted biological activity makes it a valuable research-grade biochemical for investigating cellular signaling pathways and enzyme function. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on drug discovery and metabolic studies.

Application

• Biochemical Research: As a selective inhibitor of cAMP phosphodiesterase for studying intracellular signal transduction mechanisms.
• Pharmaceutical Development: A reference standard and lead compound in drug discovery programs targeting phosphodiesterase enzymes.
• Enzyme Kinetics Studies: Used to characterize the activity and inhibition profiles of specific phosphodiesterase isoforms.
• Cell Biology: Tool compound for modulating cAMP levels in cell culture models to study downstream physiological effects.
• Academic Research: Key reagent for fundamental research in biochemistry, pharmacology, and molecular biology.

Basic Information

Product Name	Griseolic Acid B
CAS No.	98890-01-8
Molecular Formula	C17H16O9
Molecular Weight	364.30 g/mol
Synonyms	Griseolic Acid B; 98890-01-8; 2,4,6,8-Tetrahydroxy-3-(1-hydroxyethyl)-9-oxo-1H-xanthene-1-carboxylic Acid; cAMP Phosphodiesterase Inhibitor (Griseolic Acid B); Antibiotic GRIS-2B; Griseolic acid derivative B
EINECS	Contact for details

Quality Control

Our Griseolic Acid B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support research and development with material that meets exacting standards for biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.