Description

4,5-Didehydroisocarbacyclin is a synthetic analog of prostacyclin, a member of the prostanoid family of bioactive lipids. This compound is of significant interest in biochemical and pharmacological research due to its role as a stable, potent agonist for prostacyclin (IP) receptors. It is primarily utilized by research institutions and pharmaceutical companies engaged in cardiovascular research, inflammation studies, and the development of novel therapeutic agents targeting vascular and platelet disorders.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating prostacyclin receptor (IP) signaling pathways and vascular biology.
• Cardiovascular Drug Discovery: Serves as a key intermediate or lead compound in the development of new anti-thrombotic and vasodilatory pharmaceuticals.
• Biochemical Assays: Employed in in vitro and cell-based assays to study platelet aggregation inhibition and smooth muscle relaxation.
• Inflammation and Immunology Studies: Applied in research exploring the role of prostanoids in inflammatory responses and immune modulation.
• Academic Research: A critical tool for universities and research laboratories focusing on eicosanoid metabolism and receptor pharmacology.

Basic Information

Product Name	4,5-Didehydroisocarbacyclin
CAS No.	98676-80-3
Molecular Formula	C₂₂H₃₄O₄
Molecular Weight	362.50 g/mol
Synonyms	9-Deoxy-9α,11α-epoxy-15-cyclopentyl-16,17,18,19,20-pentanor-4,5-didehydro-PGF1α; 4,5-Didehydroisocarbacyclin; 15-Cyclopentyl-16,17,18,19,20-pentanor-4,5-didehydro-9-deoxy-9α,11α-epoxy-PGF1α; Isocarbacyclin derivative; ZK 36374 analog; Prostacyclin analog; IP receptor agonist.
EINECS	Contact for details

Quality Control

Our 4,5-Didehydroisocarbacyclin is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for advanced research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.