Description

Sq 29,548 (Potent And Specific Thromboxane A2 Receptor Antagonist) is a high-purity, potent, and selective pharmacological agent designed for advanced research and development. This compound is critical for investigating the role of thromboxane A2 (TXA2) signaling pathways in various physiological and pathological processes. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology firms focused on cardiovascular, pulmonary, and inflammatory disease models.

Application

• Pharmacological Research: As a selective TXA2 receptor antagonist for in vitro and in vivo studies to elucidate receptor function and signaling mechanisms.
• Cardiovascular Disease Models: Investigation of platelet aggregation, vasoconstriction, and atherosclerosis in preclinical research.
• Pulmonary Research: Study of bronchoconstriction and airway remodeling in conditions such as asthma.
• Inflammation and Immune Response Studies: Research into the role of TXA2 in inflammatory cascades and immune cell activation.
• Drug Discovery & Development: Serving as a reference standard or lead compound in the development of novel therapeutics targeting the TXA2 pathway.
• Biochemical Assay Development: Used in high-throughput screening (HTS) and binding assays to identify and characterize new receptor modulators.

Basic Information

Product Name	Sq 29,548 (Potent And Specific Thromboxane A2 Receptor Antagonist)
CAS No.	98672-91-4
Molecular Formula	C31H39NO5S
Molecular Weight	537.71 g/mol
Synonyms	SQ 29,548; SQ-29,548; [1S-[1α,2α(Z),3α,4α]]-7-[3-[[2-[(Phenylamino)carbonyl]hydrazino]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic Acid; (1S,2S,3R,4S)-7-[(1E,5Z)-3-[(2-Carbamoylhydrazinyl)methyl]-7-oxabicyclo[2.2.1]hept-2-yl]hept-5-enoic Acid; Thromboxane A2 Receptor Antagonist SQ 29,548; SQ29548; TXA2 Receptor Antagonist.
EINECS	Contact for details

Quality Control

Our Sq 29,548 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable performance in sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.