Description

Pregna-1,4,9(11)-Trien-20-Yn-3-One, 17-Hydroxy-16-Methyl-, (16β,17α)- (9Ci) is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical research. This compound is valued for its specific structural configuration, which is critical for developing novel therapeutic agents with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of steroidal drugs, including potential anti-inflammatory and hormonal therapies. Our supply ensures the consistent quality and reliability required for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Process Chemistry: Serves as a key starting material (KSM) or advanced intermediate in process development and optimization for scale-up.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Investigated for its interaction with steroid hormone receptors and related biological pathways.

Basic Information

Product Name	Pregna-1,4,9(11)-Trien-20-Yn-3-One, 17-Hydroxy-16-Methyl-, (16β,17α)- (9Ci)
CAS No.	98574-03-9
Molecular Formula	C22H26O2
Molecular Weight	322.44 g/mol
Synonyms	16β-Methyl-17α-hydroxy-1,4,9(11)-pregnatriene-20-yn-3-one; (16β,17α)-17-Hydroxy-16-methylpregna-1,4,9(11)-trien-20-yn-3-one; 16-Methyl-17-hydroxypregna-1,4,9(11)-trien-20-yn-3-one; Danazol Impurity; Danazol Related Compound; Steroid Intermediate 98574-03-9
EINECS	Contact for details

Quality Control

Our Pregna-1,4,9(11)-Trien-20-Yn-3-One, 17-Hydroxy-16-Methyl-, (16β,17α)- (9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting research and pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results. We support compliance with cGMP and other relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container in a well-ventilated area and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.