Description

4-Chloro-2,5-Dimethoxybenzenesulfonyl Chloride (Saltdata: Free) is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the introduction of the sulfonyl functional group into target molecules with high selectivity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drugs, including diuretics, anti-bacterials, and protease inhibitors.
• Agrochemical Synthesis: Used in the production of modern herbicides, fungicides, and insecticides that require specific sulfonyl moiety incorporation.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating sulfonated dyes and specialty colorants with enhanced properties.
• Polymer Chemistry: Employed in the modification of polymers to introduce sulfonyl groups, altering solubility and thermal characteristics.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in exploring new chemical entities and optimizing synthetic routes.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	4-Chloro-2,5-Dimethoxybenzenesulfonyl Chloride (Saltdata: Free)
CAS No.	98546-13-5
Molecular Formula	C8H8Cl2O4S
Molecular Weight	271.12 g/mol
Synonyms	1-Chloro-4,7-dimethoxy-2,1-benzoxathiole 2,2-dioxide; 2,5-Dimethoxy-4-chlorobenzenesulfonyl chloride; 4-Chloro-2,5-dimethoxybenzene-1-sulfonyl chloride; 4-Chloro-2,5-dimethoxybenzenesulfonylchloride; 4-Chloro-2,5-dimethoxy-phenylsulfonyl chloride; Benzenesulfonyl chloride, 4-chloro-2,5-dimethoxy-; 98546-13-5
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,5-Dimethoxybenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.