Description

2,4-Dinitrophenyl Dextran is a chemically modified polysaccharide derivative where dextran is conjugated with 2,4-dinitrophenyl (DNP) groups. This compound is significant as a well-characterized hapten-carrier conjugate, widely utilized in immunological research and assay development. It is essential for scientists and manufacturers in the fields of immunology, diagnostics, and biopharmaceutical development who require a stable, high-affinity antigen for antibody production, calibration, and inhibition studies.

Application

• Immunological Research: Serves as a standard antigen or hapten-carrier complex for studying antibody-antigen interactions, immune response mechanisms, and hypersensitivity.
• Diagnostic Assay Development: Used in the calibration and validation of immunoassays (e.g., ELISA, lateral flow tests) for the detection of anti-DNP antibodies.
• Vaccine Adjuvant Studies: Employed as a model antigen in research focused on novel vaccine formulations and adjuvant efficacy testing.
• Cell Labeling & Tracking: Functions as a fluorescent or detectable tag for cell surface labeling and tracking in flow cytometry and microscopy applications when further derivatized.
• Bioconjugation & Protein Chemistry: Acts as a versatile intermediate for further chemical modifications and the creation of more complex bioconjugates due to the reactivity of the dinitrophenyl group.
• Quality Control & Standardization: Provides a consistent and defined antigenic standard for quality control in antibody production and diagnostic kit manufacturing.

Basic Information

Product Name	2,4-Dinitrophenyl Dextran
CAS No.	98242-54-7
Molecular Formula	(C6H10O5)n with C6H3N2O5R substituents
Molecular Weight	Variable (depends on dextran chain length and degree of substitution)
Synonyms	DNP-Dextran; Dinitrophenylated Dextran; Dextran, 2,4-dinitrophenyl-; 2,4-DNP-Dextran; Dinitrophenyl Dextran; Anti-DNP Antibody Antigen; Hapten-Carrier Conjugate; Dextran DNP conjugate
EINECS	Contact for details

Quality Control

Our 2,4-Dinitrophenyl Dextran is produced under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and performance. Key parameters such as degree of substitution (DNP groups per glucose unit), molecular weight distribution, and purity are strictly controlled. A comprehensive Certificate of Analysis (COA) detailing specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange powder or solid
Identification (IR)	Conforms to structure
Degree of Substitution (DNP/glucose)	Specified range (e.g., 0.01 - 0.1)
Dextran Backbone MW	Specified range (e.g., 10kDa, 40kDa, 70kDa)
Purity (HPLC)	≥ 95%
Moisture Content	≤ 5.0%
Solubility	Soluble in water, DMSO, alkaline aqueous solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.