Description

Mono-6-Azido-6-Deoxy-β-Cyclodextrin is a specifically functionalized derivative of β-cyclodextrin, featuring a single azido group at the 6-position of the glucose ring, which serves as a versatile click chemistry handle. This modification is critical for creating advanced supramolecular assemblies and targeted delivery systems through efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. It is essential for researchers and manufacturers in pharmaceutical development, advanced material science, and diagnostic reagent formulation who require precise molecular conjugation and controlled host-guest interactions.

Application

• Pharmaceutical Research & Drug Delivery: Acts as a key intermediate for synthesizing targeted prodrugs and creating functionalized drug carrier systems via click chemistry.
• Polymer & Material Science: Used to modify polymer chains and surfaces, enabling the creation of smart hydrogels, responsive materials, and molecularly imprinted polymers.
• Bioconjugation & Probe Development: Facilitates the site-specific labeling of biomolecules (proteins, nucleic acids) with fluorescent dyes or other reporter groups for diagnostic assays.
• Catalyst & Ligand Design: Serves as a scaffold for constructing sophisticated catalysts with enhanced selectivity and solubility in aqueous or organic media.
• Chromatography & Separation Science: Employed in the synthesis of novel stationary phases for chiral separation and affinity chromatography columns.
• Academic & Industrial R&D: A fundamental building block for exploring novel supramolecular chemistry, sensor technology, and nanotechnology applications.

Basic Information

Product Name	Mono-6-Azido-6-Deoxy-β-Cyclodextrin
CAS No.	98169-85-8
Molecular Formula	C42H69N3O34
Molecular Weight	1152.00 g/mol (approx.)
Synonyms	6A-Azido-6A-deoxy-β-cyclodextrin; 6-Monoazido-6-monodeoxy-β-cyclodextrin; β-CD-N3; 6-Azido-β-cyclodextrin; Heptakis(6-azido-6-deoxy)-β-cyclodextrin (per-substituted isomer); 6-N3-β-CD; Azido-functionalized β-cyclodextrin; 98169-85-8
EINECS	Contact for details

Quality Control

Our Mono-6-Azido-6-Deoxy-β-Cyclodextrin is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing specific results for assay, substitution degree, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Degree of Substitution (NMR)	0.9 - 1.1
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.