Description

Benzenesulfonyl Chloride, 2-Bromo-5-Nitro- is a high-purity, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and nitro substituents, makes it an exceptionally versatile reagent for introducing the benzenesulfonyl moiety into complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides with sulfonylurea or sulfonamide backbones.
• Dyestuff and Pigment Manufacturing: Acts as a reactive intermediate for creating sulfonated azo dyes and high-performance pigments.
• Polymer Modification: Employed to introduce sulfonyl chloride functional groups into polymers for enhanced properties or further chemical grafting.
• Cross-Coupling Reactions: The bromo substituent allows for participation in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Chemical Research & Development: A valuable tool for medicinal chemistry and material science research exploring new sulfonated compounds.

Basic Information

Product Name	Benzenesulfonyl Chloride, 2-Bromo-5-Nitro-
CAS No.	98130-55-3
Molecular Formula	C6H3BrClNO4S
Molecular Weight	300.51 g/mol
Synonyms	2-Bromo-5-nitrobenzenesulfonyl chloride; 1-Bromo-4-nitro-2-sulfonylchloridobenzene; 5-Nitro-2-bromobenzenesulfonyl chloride; 2-Bromo-5-nitrobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 2-bromo-5-nitro-; (2-Bromo-5-nitrophenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Benzenesulfonyl Chloride, 2-Bromo-5-Nitro- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements for synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.