Description

Lorglumide CAS NO 97964-56-2 is a selective cholecystokinin B (CCK-B) receptor antagonist. This compound is a critical research tool for investigating the role of CCK receptors in gastrointestinal physiology, satiety signaling, and neurological functions. It is primarily utilized by pharmaceutical researchers, academic institutions, and R&D laboratories focused on metabolic disorders, anxiety, and pain management pathways.

Application

• Pharmacological Research: A key reference standard and active agent for studying cholecystokinin receptor subtypes, their distribution, and physiological roles.
• Gastrointestinal Studies: Used in experimental models to investigate gastric acid secretion, pancreatic enzyme release, and gallbladder motility.
• Neuroscience Research: Applied in studies exploring the modulation of anxiety, panic, and nociception (pain perception) mediated by CCK-B receptors in the central nervous system.
• Drug Discovery & Development: Serves as a lead compound or benchmark for developing novel therapeutic agents targeting CCK-related pathways for metabolic and CNS disorders.
• Biochemical Assays: Employed in in vitro receptor binding assays and functional studies to characterize new chemical entities and screen for CCK-B receptor activity.

Basic Information

Product Name	Lorglumide
CAS No.	97964-56-2
Molecular Formula	C23H30N2O5S
Molecular Weight	446.56 g/mol
Synonyms	CR-1409; Lorglumide Sodium; N-(3,4-Dichlorobenzoyl)-L-glutamic acid dipentylamide; 4-[[(2S)-2-[[(3,4-Dichlorophenyl)carbonyl]amino]pentanoyl]amino]-5-oxo-5-(pentylamino)pentanoic acid; CR1409; Lorglumide (free acid)
EINECS	Contact for details

Quality Control

Our Lorglumide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and mass spectrometry, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.