Description

Tomoglumide is a high-purity, non-peptide cholecystokinin (CCK) receptor antagonist used in advanced pharmaceutical research and development. This compound is critical for studying gastrointestinal physiology, pancreatic secretion, and satiety mechanisms, offering significant value in the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and contract manufacturing organizations (CMOs) focused on metabolic and digestive system disorders.

Application

• Pharmaceutical Research: As a selective CCK-A receptor antagonist for investigating gastrointestinal motility and pancreatic function.
• Drug Discovery: A key reference standard and intermediate in the development of new therapies for pancreatitis, irritable bowel syndrome (IBS), and obesity.
• Biochemical Assays: Used in in vitro and in vivo studies to elucidate the role of cholecystokinin in physiological and pathological processes.
• Academic Studies: Employed in university and institutional research projects focused on neurogastroenterology and appetite regulation.
• Preclinical Development: Serves as a pharmacological tool for proof-of-concept and efficacy studies in animal models.

Basic Information

Product Name	Tomoglumide
CAS No.	97964-54-0
Molecular Formula	C17H25N3O4S
Molecular Weight	367.46 g/mol
Synonyms	CR 1392; CR-1392; L-364,718; L364718; Devazepide; (3S)-1,3-Dihydro-3-[(3S)-3-(1H-indol-3-ylmethyl)-2-oxo-5-phenyl-1,4-benzodiazepin-1-yl]-2H-1,4-benzodiazepin-2-one; 1,4-Benzodiazepine-2-one, 1,3-dihydro-3-[(3S)-3-(1H-indol-3-ylmethyl)-2-oxo-5-phenyl-1,4-benzodiazepin-1-yl]-, (3S)-
EINECS	Contact for details

Quality Control

Our Tomoglumide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of the global pharmaceutical research community.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.